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Large domain movements upon UvrD dimerization and helicase activation
Binh Nguyen
, Yerdos Ordabayev
, Joshua E. Sokoloski
, Elizabeth Weiland
,
Timothy M. Lohman
Department of Biochemistry & Molecular Biophysics
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
Institute of Clinical and Translational Sciences (ICTS)
Siteman Cancer Center
Research output
:
Contribution to journal
›
Article
›
peer-review
36
Scopus citations
Overview
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Keyphrases
Dimerization
100%
UvrD
100%
Helicase Activity
100%
Domain Movement
100%
Large Domain
100%
Conformational States
25%
Escherichia Coli
16%
Helicase
16%
Translocated
8%
Single-stranded DNA (ssDNA)
8%
Interconversion
8%
Total Internal Reflection Fluorescence Microscopy
8%
DNA Substrates
8%
DNA Helicase
8%
Duplex DNA
8%
Direct Interaction
8%
Fluorescently Labeled
8%
Single Molecule
8%
Self-assembly
8%
Closed State
8%
Accessory Protein
8%
DNA Repair Capacity
8%
Activation Mechanism
8%
Open State
8%
Multiple Conformations
8%
Open Conformation
8%
Intermediate State
8%
Closed Conformation
8%
Biochemistry, Genetics and Molecular Biology
Helicase
100%
Dimerization
100%
Conformation
62%
Escherichia coli
25%
DNA Repair
12%
Fluorescence Microscopy
12%