This chapter discusses the operative technique involved with a transperitoneal laparoscopic radical prostatectomy (LRP) followed by a review of the recent published clinical series. Recent advances in laparoscopic equipment and suturing skills has resulted in LRP becoming an acceptable option for the treatment of localized prostate cancer. The surgery is now established as a feasible option with acceptable early oncological results. LRP is a technically challenging surgery and requires advanced laparoscopic skills. Decreased blood loss and possibly shorter duration of catheterization seem to be the obvious advantages of LRP. The urinary continence following surgery appears satisfactory. Magnification and the better visualization that is provided during laparoscopy can theoretically result in more accurate dissection. This can result in a superior nerve-sparing technique. The LRP is a minimally invasive option with encouraging early results for the treatment of localized prostate cancer. The LRP should, therefore, be studied prospectively in several large centers before it becomes an accepted option for the treatment of localized prostate cancer.