Laminins

Daniel G.K. Rasmussen; Jeffrey H. Miner; Marta Alexdottir; M. A. Karsdal

doi:10.1016/B978-0-443-15617-5.00037-8

Laminins

Daniel G.K. Rasmussen, Jeffrey H. Miner, Marta Alexdottir, M. A. Karsdal

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

This chapter introduces a large protein family named laminins that are intimately involved in the correct assembly of the basement membrane. The chapter starts by describing laminin structures and nomenclature, followed by detailing key interaction partners in the basement membrane, and finally describes its signaling properties. It then moves into details of specific laminin types, examples of laminin mutations and their implications in humans, and finally describes key features of individual laminin subchains.

Original language	English
Title of host publication	Biochemistry of Collagens, Laminins and Elastin
Subtitle of host publication	Structure, Function and Biomarkers, Third Edition
Publisher	Elsevier
Pages	227-277
Number of pages	51
ISBN (Electronic)	9780443156175
ISBN (Print)	9780443156182
DOIs	https://doi.org/10.1016/B978-0-443-15617-5.00037-8
State	Published - Jan 1 2023

Keywords

Basement membrane
Development
Epidermolysis bullosa
Extracellular matrix
Laminin
Lethal
Pierson syndrome

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10.1016/B978-0-443-15617-5.00037-8

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AU - Rasmussen, Daniel G.K.

AU - Miner, Jeffrey H.

AU - Alexdottir, Marta

AU - Karsdal, M. A.

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N2 - This chapter introduces a large protein family named laminins that are intimately involved in the correct assembly of the basement membrane. The chapter starts by describing laminin structures and nomenclature, followed by detailing key interaction partners in the basement membrane, and finally describes its signaling properties. It then moves into details of specific laminin types, examples of laminin mutations and their implications in humans, and finally describes key features of individual laminin subchains.

AB - This chapter introduces a large protein family named laminins that are intimately involved in the correct assembly of the basement membrane. The chapter starts by describing laminin structures and nomenclature, followed by detailing key interaction partners in the basement membrane, and finally describes its signaling properties. It then moves into details of specific laminin types, examples of laminin mutations and their implications in humans, and finally describes key features of individual laminin subchains.

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KW - Development

KW - Epidermolysis bullosa

KW - Extracellular matrix

KW - Laminin

KW - Lethal

KW - Pierson syndrome

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SN - 9780443156182

SP - 227

EP - 277

BT - Biochemistry of Collagens, Laminins and Elastin

PB - Elsevier

ER -

Laminins

Abstract

Keywords

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