Kinetic resolution of N-acyl-thiolactams via catalytic enantioselective deacylation

Valentina D. Bumbu; Xing Yang; Vladimir B. Birman

doi:10.1021/ol401122g

Kinetic resolution of N-acyl-thiolactams via catalytic enantioselective deacylation

Valentina D. Bumbu, Xing Yang, Vladimir B. Birman

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Methanolysis of N-acyl-thiazolidin-2-thiones and -oxazolidin-2-thiones in the presence of acyl transfer catalyst benzotetramisole (BTM) proceeds in a highly enantioselective fashion thus enabling kinetic resolution of these substrates.

Original language	English
Pages (from-to)	2790-2793
Number of pages	4
Journal	Organic Letters
Volume	15
Issue number	11
DOIs	https://doi.org/10.1021/ol401122g
State	Published - Jun 7 2013

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10.1021/ol401122g

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title = "Kinetic resolution of N-acyl-thiolactams via catalytic enantioselective deacylation",

abstract = "Methanolysis of N-acyl-thiazolidin-2-thiones and -oxazolidin-2-thiones in the presence of acyl transfer catalyst benzotetramisole (BTM) proceeds in a highly enantioselective fashion thus enabling kinetic resolution of these substrates.",

author = "Bumbu, {Valentina D.} and Xing Yang and Birman, {Vladimir B.}",

year = "2013",

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journal = "Organic Letters",

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T1 - Kinetic resolution of N-acyl-thiolactams via catalytic enantioselective deacylation

AU - Bumbu, Valentina D.

AU - Yang, Xing

AU - Birman, Vladimir B.

PY - 2013/6/7

Y1 - 2013/6/7

N2 - Methanolysis of N-acyl-thiazolidin-2-thiones and -oxazolidin-2-thiones in the presence of acyl transfer catalyst benzotetramisole (BTM) proceeds in a highly enantioselective fashion thus enabling kinetic resolution of these substrates.

AB - Methanolysis of N-acyl-thiazolidin-2-thiones and -oxazolidin-2-thiones in the presence of acyl transfer catalyst benzotetramisole (BTM) proceeds in a highly enantioselective fashion thus enabling kinetic resolution of these substrates.

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U2 - 10.1021/ol401122g

DO - 10.1021/ol401122g

M3 - Article

AN - SCOPUS:84879227115

SN - 1523-7060

VL - 15

SP - 2790

EP - 2793

JO - Organic Letters

JF - Organic Letters

IS - 11

ER -

Kinetic resolution of N-acyl-thiolactams via catalytic enantioselective deacylation

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