Kinetic resolution of β-lactams via enantioselective N-acylation

Xing Yang; Valentina D. Bumbu; Vladimir B. Birman

doi:10.1021/ol201911z

Kinetic resolution of β-lactams via enantioselective N-acylation

Xing Yang
, Valentina D. Bumbu
, Vladimir B. Birman

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

Enantioselective N-acylation of 4-aryl-β-lactams in the presence of acyl transfer catalyst Cl-PIQ provides an effective method for their non-enzymatic kinetic resolution.

Original language	English
Pages (from-to)	4755-4757
Number of pages	3
Journal	Organic Letters
Volume	13
Issue number	18
DOIs	https://doi.org/10.1021/ol201911z
State	Published - Sep 16 2011

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title = "Kinetic resolution of β-lactams via enantioselective N-acylation",

abstract = "Enantioselective N-acylation of 4-aryl-β-lactams in the presence of acyl transfer catalyst Cl-PIQ provides an effective method for their non-enzymatic kinetic resolution.",

author = "Xing Yang and Bumbu, \{Valentina D.\} and Birman, \{Vladimir B.\}",

year = "2011",

month = sep,

day = "16",

doi = "10.1021/ol201911z",

language = "English",

volume = "13",

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journal = "Organic Letters",

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AU - Yang, Xing

AU - Bumbu, Valentina D.

AU - Birman, Vladimir B.

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Y1 - 2011/9/16

N2 - Enantioselective N-acylation of 4-aryl-β-lactams in the presence of acyl transfer catalyst Cl-PIQ provides an effective method for their non-enzymatic kinetic resolution.

AB - Enantioselective N-acylation of 4-aryl-β-lactams in the presence of acyl transfer catalyst Cl-PIQ provides an effective method for their non-enzymatic kinetic resolution.

UR - https://www.scopus.com/pages/publications/80052748526

U2 - 10.1021/ol201911z

DO - 10.1021/ol201911z

M3 - Article

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AN - SCOPUS:80052748526

SN - 1523-7060

VL - 13

SP - 4755

EP - 4757

JO - Organic Letters

JF - Organic Letters

IS - 18

ER -

Kinetic resolution of β-lactams via enantioselective N-acylation

Abstract

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