TY - JOUR
T1 - Isolated laryngeal leishmaniasis in a 55-year-old man with dysphonia and rheumatoid arthritis
T2 - Case report and literature review
AU - Strazzulla, Alessio
AU - Cocuzza, Salvatore
AU - Pinzone, Marilia Rita
AU - Francesco, Martines
AU - Serra, Agostino
AU - Cosentino, Stefano
AU - Cacopardo, Bruno
AU - Nunnari, Giuseppe
PY - 2013
Y1 - 2013
N2 - We describe a case of isolated laryngeal leishmaniasis in an 55-year-old smoker, treated with steroids for rheumatoid arthritis, in the absence of concomitant visceral or cutaneous localizations. Clinical presentation was dominated by dysphonia. Laryngeal biopsy revealed the presence of Leishmania amastigotes, which were characterized by species-specific polymerase chain reaction as L. donovani parasites. In endemic areas, Leishmania infection may present with atypical localizations and it has to be considered as a possible cause of laryngeal symptoms, especially in subjects with known immunosuppressive diseases or under treatment with immunosuppressive drugs.
AB - We describe a case of isolated laryngeal leishmaniasis in an 55-year-old smoker, treated with steroids for rheumatoid arthritis, in the absence of concomitant visceral or cutaneous localizations. Clinical presentation was dominated by dysphonia. Laryngeal biopsy revealed the presence of Leishmania amastigotes, which were characterized by species-specific polymerase chain reaction as L. donovani parasites. In endemic areas, Leishmania infection may present with atypical localizations and it has to be considered as a possible cause of laryngeal symptoms, especially in subjects with known immunosuppressive diseases or under treatment with immunosuppressive drugs.
KW - Laryngeal lesion
KW - Leishmania
KW - Leishmaniasis
KW - Rheumathoid arthritis
UR - http://www.scopus.com/inward/record.url?scp=84896705673&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:84896705673
SN - 0393-6384
VL - 29
SP - 807
EP - 810
JO - Acta Medica Mediterranea
JF - Acta Medica Mediterranea
IS - 4
ER -