Ischemic Heart Disease in Young Women: JACC Review Topic of the Week

Margo B. Minissian; Puja K. Mehta; Sharonne N. Hayes; Ki Park; Janet Wei; C. Noel Bairey Merz; Leslie Cho; Annabelle Santos Volgman; Islam Y. Elgendy; Mamas Mamas; Melinda B. Davis; Harmony R. Reynolds; Kelly Epps; Kathryn Lindley; Malissa Wood; Odayme Quesada; Gregory Piazza; Carl J. Pepine

doi:10.1016/j.jacc.2022.01.057

Ischemic Heart Disease in Young Women: JACC Review Topic of the Week

Margo B. Minissian, Puja K. Mehta, Sharonne N. Hayes, Ki Park, Janet Wei, C. Noel Bairey Merz, Leslie Cho, Annabelle Santos Volgman, Islam Y. Elgendy, Mamas Mamas, Melinda B. Davis, Harmony R. Reynolds, Kelly Epps, Kathryn Lindley, Malissa Wood, Odayme Quesada, Gregory Piazza, Carl J. Pepine

Research output: Contribution to journal › Review article › peer-review

23 Scopus citations

Abstract

The Cardiovascular Disease in Women Committee of the American College of Cardiology convened a working group to develop a consensus regarding the continuing rise of mortality rates in young women aged 35 to 54 years. Heart disease mortality rates in young women continue to increase. Young women have increased mortality secondary to ischemic heart disease (IHD) compared with comparably aged men and similar mortality to that observed among older women. The authors reviewed the published evidence, including observational and mechanistic/translational data, and identified knowledge gaps pertaining to young women. This paper provides clinicians with pragmatic, evidence-based management strategies for young women at risk for IHD. Next-step research opportunities are outlined. This report presents highlights of the working group review and a summary of suggested research directions to advance the IHD field in the next decade.

Original language	English
Pages (from-to)	1014-1022
Number of pages	9
Journal	Journal of the American College of Cardiology
Volume	80
Issue number	10
DOIs	https://doi.org/10.1016/j.jacc.2022.01.057
State	Published - Sep 6 2022

Keywords

disease
heart
ischemic
mortality
women

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10.1016/j.jacc.2022.01.057

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Minissian, M. B., Mehta, P. K., Hayes, S. N., Park, K., Wei, J., Bairey Merz, C. N., Cho, L., Volgman, A. S., Elgendy, I. Y., Mamas, M., Davis, M. B., Reynolds, H. R., Epps, K., Lindley, K., Wood, M., Quesada, O., Piazza, G., & Pepine, C. J. (2022). Ischemic Heart Disease in Young Women: JACC Review Topic of the Week. Journal of the American College of Cardiology, 80(10), 1014-1022. https://doi.org/10.1016/j.jacc.2022.01.057

@article{5fede55260a247d2b98700921a136070,

title = "Ischemic Heart Disease in Young Women: JACC Review Topic of the Week",

abstract = "The Cardiovascular Disease in Women Committee of the American College of Cardiology convened a working group to develop a consensus regarding the continuing rise of mortality rates in young women aged 35 to 54 years. Heart disease mortality rates in young women continue to increase. Young women have increased mortality secondary to ischemic heart disease (IHD) compared with comparably aged men and similar mortality to that observed among older women. The authors reviewed the published evidence, including observational and mechanistic/translational data, and identified knowledge gaps pertaining to young women. This paper provides clinicians with pragmatic, evidence-based management strategies for young women at risk for IHD. Next-step research opportunities are outlined. This report presents highlights of the working group review and a summary of suggested research directions to advance the IHD field in the next decade.",

keywords = "disease, heart, ischemic, mortality, women",

author = "Minissian, {Margo B.} and Mehta, {Puja K.} and Hayes, {Sharonne N.} and Ki Park and Janet Wei and {Bairey Merz}, {C. Noel} and Leslie Cho and Volgman, {Annabelle Santos} and Elgendy, {Islam Y.} and Mamas Mamas and Davis, {Melinda B.} and Reynolds, {Harmony R.} and Kelly Epps and Kathryn Lindley and Malissa Wood and Odayme Quesada and Gregory Piazza and Pepine, {Carl J.}",

note = "Publisher Copyright: {\textcopyright} 2022",

year = "2022",

month = sep,

day = "6",

doi = "10.1016/j.jacc.2022.01.057",

language = "English",

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Minissian, MB, Mehta, PK, Hayes, SN, Park, K, Wei, J, Bairey Merz, CN, Cho, L, Volgman, AS, Elgendy, IY, Mamas, M, Davis, MB, Reynolds, HR, Epps, K, Lindley, K, Wood, M, Quesada, O, Piazza, G & Pepine, CJ 2022, 'Ischemic Heart Disease in Young Women: JACC Review Topic of the Week', Journal of the American College of Cardiology, vol. 80, no. 10, pp. 1014-1022. https://doi.org/10.1016/j.jacc.2022.01.057

TY - JOUR

T1 - Ischemic Heart Disease in Young Women

T2 - JACC Review Topic of the Week

AU - Minissian, Margo B.

AU - Mehta, Puja K.

AU - Hayes, Sharonne N.

AU - Park, Ki

AU - Wei, Janet

AU - Bairey Merz, C. Noel

AU - Cho, Leslie

AU - Volgman, Annabelle Santos

AU - Elgendy, Islam Y.

AU - Mamas, Mamas

AU - Davis, Melinda B.

AU - Reynolds, Harmony R.

AU - Epps, Kelly

AU - Lindley, Kathryn

AU - Wood, Malissa

AU - Quesada, Odayme

AU - Piazza, Gregory

AU - Pepine, Carl J.

PY - 2022/9/6

Y1 - 2022/9/6

N2 - The Cardiovascular Disease in Women Committee of the American College of Cardiology convened a working group to develop a consensus regarding the continuing rise of mortality rates in young women aged 35 to 54 years. Heart disease mortality rates in young women continue to increase. Young women have increased mortality secondary to ischemic heart disease (IHD) compared with comparably aged men and similar mortality to that observed among older women. The authors reviewed the published evidence, including observational and mechanistic/translational data, and identified knowledge gaps pertaining to young women. This paper provides clinicians with pragmatic, evidence-based management strategies for young women at risk for IHD. Next-step research opportunities are outlined. This report presents highlights of the working group review and a summary of suggested research directions to advance the IHD field in the next decade.

AB - The Cardiovascular Disease in Women Committee of the American College of Cardiology convened a working group to develop a consensus regarding the continuing rise of mortality rates in young women aged 35 to 54 years. Heart disease mortality rates in young women continue to increase. Young women have increased mortality secondary to ischemic heart disease (IHD) compared with comparably aged men and similar mortality to that observed among older women. The authors reviewed the published evidence, including observational and mechanistic/translational data, and identified knowledge gaps pertaining to young women. This paper provides clinicians with pragmatic, evidence-based management strategies for young women at risk for IHD. Next-step research opportunities are outlined. This report presents highlights of the working group review and a summary of suggested research directions to advance the IHD field in the next decade.

KW - disease

KW - heart

KW - ischemic

KW - mortality

KW - women

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DO - 10.1016/j.jacc.2022.01.057

M3 - Review article

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AN - SCOPUS:85136284442

SN - 0735-1097

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JO - Journal of the American College of Cardiology

JF - Journal of the American College of Cardiology

IS - 10

ER -

Ischemic Heart Disease in Young Women: JACC Review Topic of the Week

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