Is Zero Ventilator-Associated Pneumonia Achievable? Practical Approaches to Ventilator-Associated Pneumonia Prevention

Research output: Contribution to journalReview article

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Abstract

Ventilator-associated pneumonia (VAP) remains a significant clinical entity with reported incidence rates of 7% to 15%. Given the considerable adverse consequences associated with this infection, VAP prevention became a core measure required in most US hospitals. Many institutions implemented effective VAP prevention bundles that combined head of bed elevation, hand hygiene, chlorhexidine oral care, and subglottic drainage. More recently, spontaneous breathing and awakening trials have consistently been shown to shorten the duration of mechanical ventilation and secondarily reduce the occurrence of VAP. More recent data question the overall positive impact of prevention bundles, including some of their core component interventions.

Original languageEnglish
Pages (from-to)809-822
Number of pages14
JournalClinics in Chest Medicine
Volume39
Issue number4
DOIs
StatePublished - Dec 2018

Keywords

  • Antimicrobial resistance
  • Chlorhexidine
  • Prevention bundle
  • Selective digestive decontamination
  • Ventilator-associated pneumonia

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