Is there a high-risk subtype of depression in patients with coronary heart disease?

Robert M. Carney, Kenneth E. Freedland

Research output: Contribution to journalReview articlepeer-review

34 Scopus citations


Depression is a risk factor for cardiac morbidity and mortality in patients with coronary heart disease, especially in those with a recent history of acute coronary syndrome. To improve risk stratification and treatment planning, it would be useful to identify the characteristics or subtypes of depression that are associated with the highest risk of cardiac events. This paper reviews the evidence concerning several putative depression subtypes and symptom patterns that may be associated with a high risk of morbidity and mortality in cardiac patients, including single-episode major depressive disorder, depression that emerges after a cardiac event, somatic symptoms of depression, and treatment-resistant depression.

Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalCurrent psychiatry reports
Issue number1
StatePublished - Feb 2012


  • Coronary disease
  • Coronary heart disease
  • Depression
  • Depressive disorder
  • High risk
  • Major depressive disorder
  • Mortality
  • Myocardial infarction
  • Myocardial ischemia
  • Subtype
  • Treatment-resistant depression


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