Abstract

Obesity disrupts physiological homeostasis and alters both systemic and local microenvironments that impact stem cell plasticity and impair regenerative capacity. We present growing evidence that reveals the bidirectionality of obesity-induced stem cell dysfunction and how the molecular changes in stem cells residing in obese environments may accelerate disease severity.

Original languageEnglish
Pages (from-to)15-18
Number of pages4
JournalCell Stem Cell
Volume27
Issue number1
DOIs
StatePublished - Jul 2 2020

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