Irrigation and debridement for periprosthetic infections: Does the organism matter?

Susan M. Odum; Thomas K. Fehring; Adolph V. Lombardi; Ben M. Zmistowski; Nicholas M. Brown; Jeffrey T. Luna; Keith A. Fehring; Erik N. Hansen; Keith R. Berend; Kevin J. Bozic; Craig J.Della Valle; Terence J. Gioe; William A. Jiranek; Javad Parvizi; Bryan D. Springer

doi:10.1016/j.arth.2011.03.031

Irrigation and debridement for periprosthetic infections: Does the organism matter?

Susan M. Odum
, Thomas K. Fehring
, Adolph V. Lombardi
, Ben M. Zmistowski
, Nicholas M. Brown
, Jeffrey T. Luna
, Keith A. Fehring
, Erik N. Hansen
, Keith R. Berend
, Kevin J. Bozic
, Craig J.Della Valle
, Terence J. Gioe
, William A. Jiranek
, Javad Parvizi
, Bryan D. Springer

Division of Shoulder & Elbow

Research output: Contribution to journal › Article › peer-review

130 Scopus citations

Abstract

Irrigation and debridement (I&D) is an attractive treatment alternative for periprosthetic joint infection (PJI). Irrigation and debridement failure rates average 64% (range, 10.5%-84%) and may be associated with causative organism type and virulence. The study objective was to compare revision rates for PJI caused by streptococcal organisms to other organisms treated with I&D. A multicenter retrospective cohort study of 200 consecutive PJIs treated with I&D was performed. Failure was defined as reoperation for PJI. Failure rate for streptococcal infections was 65% (20/31) compared with 71% (84/119) for other organisms. Failure rate for sensitive Staphylococcus was 72% (48/67) compared with a 76% (22/29) failure rate for resistant Staphylococcus. These results indicate that eradication rates of I&D for a streptococcal PJI are comparable with other causative organisms. Irrigation and debridement should play a limited role in the PJI treatment algorithm regardless of organism type.

Original language	English
Pages (from-to)	114-118
Number of pages	5
Journal	Journal of Arthroplasty
Volume	26
Issue number	SUPPL. 6
DOIs	https://doi.org/10.1016/j.arth.2011.03.031
State	Published - Sep 2011

Keywords

Causative organism
Periprosthetic joint infection
Revision arthroplasty

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10.1016/j.arth.2011.03.031

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Odum, S. M., Fehring, T. K., Lombardi, A. V., Zmistowski, B. M., Brown, N. M., Luna, J. T., Fehring, K. A., Hansen, E. N., Berend, K. R., Bozic, K. J., Valle, C. J. D., Gioe, T. J., Jiranek, W. A., Parvizi, J., & Springer, B. D. (2011). Irrigation and debridement for periprosthetic infections: Does the organism matter? Journal of Arthroplasty, 26(SUPPL. 6), 114-118. https://doi.org/10.1016/j.arth.2011.03.031

@article{2d2040b5198a46a3a08d86953d03aea4,

title = "Irrigation and debridement for periprosthetic infections: Does the organism matter?",

abstract = "Irrigation and debridement (I\&D) is an attractive treatment alternative for periprosthetic joint infection (PJI). Irrigation and debridement failure rates average 64\% (range, 10.5\%-84\%) and may be associated with causative organism type and virulence. The study objective was to compare revision rates for PJI caused by streptococcal organisms to other organisms treated with I\&D. A multicenter retrospective cohort study of 200 consecutive PJIs treated with I\&D was performed. Failure was defined as reoperation for PJI. Failure rate for streptococcal infections was 65\% (20/31) compared with 71\% (84/119) for other organisms. Failure rate for sensitive Staphylococcus was 72\% (48/67) compared with a 76\% (22/29) failure rate for resistant Staphylococcus. These results indicate that eradication rates of I\&D for a streptococcal PJI are comparable with other causative organisms. Irrigation and debridement should play a limited role in the PJI treatment algorithm regardless of organism type.",

keywords = "Causative organism, Periprosthetic joint infection, Revision arthroplasty",

author = "Odum, \{Susan M.\} and Fehring, \{Thomas K.\} and Lombardi, \{Adolph V.\} and Zmistowski, \{Ben M.\} and Brown, \{Nicholas M.\} and Luna, \{Jeffrey T.\} and Fehring, \{Keith A.\} and Hansen, \{Erik N.\} and Berend, \{Keith R.\} and Bozic, \{Kevin J.\} and Valle, \{Craig J.Della\} and Gioe, \{Terence J.\} and Jiranek, \{William A.\} and Javad Parvizi and Springer, \{Bryan D.\}",

year = "2011",

month = sep,

doi = "10.1016/j.arth.2011.03.031",

language = "English",

volume = "26",

pages = "114--118",

journal = "Journal of Arthroplasty",

issn = "0883-5403",

number = "SUPPL. 6",

}

Odum, SM, Fehring, TK, Lombardi, AV, Zmistowski, BM, Brown, NM, Luna, JT, Fehring, KA, Hansen, EN, Berend, KR, Bozic, KJ, Valle, CJD, Gioe, TJ, Jiranek, WA, Parvizi, J & Springer, BD 2011, 'Irrigation and debridement for periprosthetic infections: Does the organism matter?', Journal of Arthroplasty, vol. 26, no. SUPPL. 6, pp. 114-118. https://doi.org/10.1016/j.arth.2011.03.031

TY - JOUR

T1 - Irrigation and debridement for periprosthetic infections

T2 - Does the organism matter?

AU - Odum, Susan M.

AU - Fehring, Thomas K.

AU - Lombardi, Adolph V.

AU - Zmistowski, Ben M.

AU - Brown, Nicholas M.

AU - Luna, Jeffrey T.

AU - Fehring, Keith A.

AU - Hansen, Erik N.

AU - Berend, Keith R.

AU - Bozic, Kevin J.

AU - Valle, Craig J.Della

AU - Gioe, Terence J.

AU - Jiranek, William A.

AU - Parvizi, Javad

AU - Springer, Bryan D.

PY - 2011/9

Y1 - 2011/9

N2 - Irrigation and debridement (I&D) is an attractive treatment alternative for periprosthetic joint infection (PJI). Irrigation and debridement failure rates average 64% (range, 10.5%-84%) and may be associated with causative organism type and virulence. The study objective was to compare revision rates for PJI caused by streptococcal organisms to other organisms treated with I&D. A multicenter retrospective cohort study of 200 consecutive PJIs treated with I&D was performed. Failure was defined as reoperation for PJI. Failure rate for streptococcal infections was 65% (20/31) compared with 71% (84/119) for other organisms. Failure rate for sensitive Staphylococcus was 72% (48/67) compared with a 76% (22/29) failure rate for resistant Staphylococcus. These results indicate that eradication rates of I&D for a streptococcal PJI are comparable with other causative organisms. Irrigation and debridement should play a limited role in the PJI treatment algorithm regardless of organism type.

AB - Irrigation and debridement (I&D) is an attractive treatment alternative for periprosthetic joint infection (PJI). Irrigation and debridement failure rates average 64% (range, 10.5%-84%) and may be associated with causative organism type and virulence. The study objective was to compare revision rates for PJI caused by streptococcal organisms to other organisms treated with I&D. A multicenter retrospective cohort study of 200 consecutive PJIs treated with I&D was performed. Failure was defined as reoperation for PJI. Failure rate for streptococcal infections was 65% (20/31) compared with 71% (84/119) for other organisms. Failure rate for sensitive Staphylococcus was 72% (48/67) compared with a 76% (22/29) failure rate for resistant Staphylococcus. These results indicate that eradication rates of I&D for a streptococcal PJI are comparable with other causative organisms. Irrigation and debridement should play a limited role in the PJI treatment algorithm regardless of organism type.

KW - Causative organism

KW - Periprosthetic joint infection

KW - Revision arthroplasty

UR - https://www.scopus.com/pages/publications/84868301811

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DO - 10.1016/j.arth.2011.03.031

M3 - Article

AN - SCOPUS:84868301811

SN - 0883-5403

VL - 26

SP - 114

EP - 118

JO - Journal of Arthroplasty

JF - Journal of Arthroplasty

IS - SUPPL. 6

ER -

Irrigation and debridement for periprosthetic infections: Does the organism matter?

Abstract

Keywords

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