Irrigation and debridement for periprosthetic infections: Does the organism matter?

Susan M. Odum, Thomas K. Fehring, Adolph V. Lombardi, Ben M. Zmistowski, Nicholas M. Brown, Jeffrey T. Luna, Keith A. Fehring, Erik N. Hansen, Keith R. Berend, Kevin J. Bozic, Craig J.Della Valle, Terence J. Gioe, William A. Jiranek, Javad Parvizi, Bryan D. Springer

Research output: Contribution to journalArticlepeer-review

120 Scopus citations


Irrigation and debridement (I&D) is an attractive treatment alternative for periprosthetic joint infection (PJI). Irrigation and debridement failure rates average 64% (range, 10.5%-84%) and may be associated with causative organism type and virulence. The study objective was to compare revision rates for PJI caused by streptococcal organisms to other organisms treated with I&D. A multicenter retrospective cohort study of 200 consecutive PJIs treated with I&D was performed. Failure was defined as reoperation for PJI. Failure rate for streptococcal infections was 65% (20/31) compared with 71% (84/119) for other organisms. Failure rate for sensitive Staphylococcus was 72% (48/67) compared with a 76% (22/29) failure rate for resistant Staphylococcus. These results indicate that eradication rates of I&D for a streptococcal PJI are comparable with other causative organisms. Irrigation and debridement should play a limited role in the PJI treatment algorithm regardless of organism type.

Original languageEnglish
Pages (from-to)114-118
Number of pages5
JournalJournal of Arthroplasty
Issue numberSUPPL. 6
StatePublished - Sep 2011


  • Causative organism
  • Periprosthetic joint infection
  • Revision arthroplasty


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