Ionizing radiation for tumor-targeted drug delivery

Roberto Diaz; Li Zhou; Dennis E. Hallahan

doi:10.1201/9781420087734

Ionizing radiation for tumor-targeted drug delivery

Roberto Diaz, Li Zhou, Dennis E. Hallahan

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Current treatments of solid tumors often involve using both chemotherapy and radiotherapy in parallel. Concomitant chemotherapy and radiation therapy is the standard of care for patients with advanced (stages III and IV) head and neck cancer1,2 and non-small-cell lung cancer.^3,4Chemotherapeutic agents generally utilized include radiosensitizing agents like taxanes (e.g., paclitaxel) and platinum compounds (e.g., carboplatin). This approach has improved local control and median survival in these patients.

Original language	English
Title of host publication	Targeted Delivery of Small and Macromolecular Drugs
Publisher	CRC Press
Pages	53-82
Number of pages	30
ISBN (Electronic)	9781420087734
ISBN (Print)	9781420087727
DOIs	https://doi.org/10.1201/9781420087734
State	Published - Jan 1 2010

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10.1201/9781420087734

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AB - Current treatments of solid tumors often involve using both chemotherapy and radiotherapy in parallel. Concomitant chemotherapy and radiation therapy is the standard of care for patients with advanced (stages III and IV) head and neck cancer1,2 and non-small-cell lung cancer.3,4Chemotherapeutic agents generally utilized include radiosensitizing agents like taxanes (e.g., paclitaxel) and platinum compounds (e.g., carboplatin). This approach has improved local control and median survival in these patients.

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Ionizing radiation for tumor-targeted drug delivery

Abstract

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