Ionic liquids as matrices for MALDI-MS

Ying Li, Li Kang Zhang, Michael L. Gross

Research output: Contribution to conferencePaperpeer-review


The prospects of detecting and quantifying peptides and proteins were studied using ionic liquids as matrices for MALDI-MS. Ionic liquids of α-cyano-4-hydroxycinnamic acid (CHCA) were prepared by dissolving 0.5g of acid in 15 mL methanol. Bradykinin and Tyr-bradykinin were chosen as test analytes and internal standards. MALDI-TOF spectra from positive and negative-ion modes verified the molecular weights of all ionic liquids.

Original languageEnglish
Number of pages2
StatePublished - 2002
EventProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States
Duration: Jun 2 2002Jun 6 2002


ConferenceProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics
Country/TerritoryUnited States
CityOrlando, FL


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