Ion Channels in the Cell Membrane: Structure, Function, and Modeling

D. Wu, J. Cui

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Ion channels are integral membrane proteins found on the membrane of all cells and play important roles in cell signaling. These ubiquitous proteins are evolutionarily conserved in elementary form and function across organisms as diverse as bacteria, flies, and humans - a testament to the fundamental necessity of ion channels for an organism's survival. Diseases linked to ion channel dysfunction, such as epilepsy, cardiac arrhythmias, cystic fibrosis, and diabetes, illustrate the importance of ion channels in physiology. This chapter will examine the structure, function, and physiological roles of ion channels with special emphasis on voltage-gated channels.

Original languageEnglish
Title of host publicationPhysical Medicine and Rehabilitation
Number of pages11
ISBN (Electronic)9780444536327
ISBN (Print)9780444536334
StatePublished - Jul 25 2014


  • Action potential
  • Cardiac myocyte
  • Ion channel
  • Neuron


Dive into the research topics of 'Ion Channels in the Cell Membrane: Structure, Function, and Modeling'. Together they form a unique fingerprint.

Cite this