TY - JOUR
T1 - Involvement of Arabidopsis HAC family genes in pleiotropic developmental processes
AU - Li, Chao
AU - Xu, Jiang
AU - Li, Jian
AU - Li, Qingyun
AU - Yang, Hongchun
N1 - Funding Information:
We thank the Arabidopsis BiologicalResources Center at the Ohio StateUniversity and Bernd Weisshaar forproviding SALK and GABI T-DNAinsertion lines in the Col-0 background. This work was supported by the Ministry of Science and Technology of China 863 project, Transgenic Program of China (2009ZX08009–065B), and the National Natural Science Foundation of China (31071351).
PY - 2014
Y1 - 2014
N2 - With intrinsic acetyltransferase activities, CREB binding protein (CBP)/p300 proteins mediate a variety of physiological events, such as proliferation, differentiation, and apoptosis, by regulating both histones and non-histone proteins. Arabidopsis CBP-type histone acetyltransferase family proteins, HACs, have been found to influence flower by regulating the expression of Flowering Locus C. We recently reported that HAC family genes involved in the ethylene signaling pathway. Thereafter, we systematically analyzed the morphological and developmental phenotypes of all the hac mutant combinations including plant size, root, flower, leaf defects, and late-flowering. Here we reinforce the ubiquitous regulation mechanism of HAC family genes, in which HAC1 plays a dominant role with the synergistic assist of HAC5 and HAC12, whereas HAC4 slightly alleviates the influence of HAC1 and HAC5.
AB - With intrinsic acetyltransferase activities, CREB binding protein (CBP)/p300 proteins mediate a variety of physiological events, such as proliferation, differentiation, and apoptosis, by regulating both histones and non-histone proteins. Arabidopsis CBP-type histone acetyltransferase family proteins, HACs, have been found to influence flower by regulating the expression of Flowering Locus C. We recently reported that HAC family genes involved in the ethylene signaling pathway. Thereafter, we systematically analyzed the morphological and developmental phenotypes of all the hac mutant combinations including plant size, root, flower, leaf defects, and late-flowering. Here we reinforce the ubiquitous regulation mechanism of HAC family genes, in which HAC1 plays a dominant role with the synergistic assist of HAC5 and HAC12, whereas HAC4 slightly alleviates the influence of HAC1 and HAC5.
KW - CBP/p300
KW - Development
KW - Ethylene
KW - HAC
KW - Histone acetyltransferase
KW - Signaling
UR - http://www.scopus.com/inward/record.url?scp=84899133590&partnerID=8YFLogxK
U2 - 10.4161/psb.28173
DO - 10.4161/psb.28173
M3 - Article
C2 - 24614176
AN - SCOPUS:84899133590
SN - 1559-2316
VL - 9
JO - Plant Signaling and Behavior
JF - Plant Signaling and Behavior
IS - MAR
M1 - e28173
ER -