Invited Review: Nutrition Support in Patients With Cancer: What Do the Data Really Show?

Samuel Klein, Ronald L. Koretz

Research output: Contribution to journalReview articlepeer-review

129 Scopus citations

Abstract

Although more than 70 prospective randomized controlled trials have evaluated the use of nutrition support in patients with cancer, the indications for nutrition therapy in this patient population remain controversial. We reviewed the published prospective randomized controlled trials that evaluated clinically important endpoints (morbidity, mortality, and duration of hospitalization). Many trials had serious shortcomings in study design that limit the ability to draw definitive conclusions from the data. In general, the data failed to demonstrate the clinical efficacy of providing nutrition support to most patients with cancer. Therefore, the indications for using nutrition therapy should be the same as those for patients with benign disease.

Original languageEnglish
Pages (from-to)91-100
Number of pages10
JournalNutrition in Clinical Practice
Volume9
Issue number3
DOIs
StatePublished - Jun 1994

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