Investigating how peptide length and a pathogenic mutation modify the structural ensemble of amyloid beta monomer

Keyphrases

• Pathogenic mutations 100%
• Amyloid beta 100%
• Structural Ensembles 100%
• Peptide Length 100%
• Alzheimer's Disease 33%
• Molecular Dynamics Simulation 33%
• Hairpin Formation 33%
• C-terminus 33%
• Structural Alterations 33%
• Protein Modeling 33%
• Tertiary Structure 33%
• Explicit Solvent 33%
• Secondary Structure 33%
• Oligomerization 33%
• Hydrophobicity 33%
• Helix Formation 33%
• All-atom 33%
• Aggregation Propensity 33%
• Water Model 33%
• Helix-helix Interaction 33%

Biochemistry, Genetics and Molecular Biology

• Amyloid Beta 100%
• C-Terminus 50%
• Solution and Solubility 50%
• Tertiary Structure 50%
• Oligomerization 50%
• Hydrophobicity 50%