Abstract

Chemotherapy is one of the treatment methods aimed at killing cancer cells and hindering their metastasis. However, chemotherapy is known to induce multiple adverse side-effects. One of them is peripheral neuropathy, which causes significant discomfort to the cancer patient. It is hypothesized that neuropathy is directly linked to peripheral nerve damage or elasticity change. In this study we have attempted to use Brillouin spectroscopy to evaluate nerve elasticity changes and correlate them to the effects of chemotherapy.

Original languageEnglish
Title of host publicationVisualizing and Quantifying Drug Distribution in Tissue VIII
EditorsKin Foong Chan, Conor L. Evans
PublisherSPIE
ISBN (Electronic)9781510669017
DOIs
StatePublished - 2024
EventVisualizing and Quantifying Drug Distribution in Tissue VIII 2024 - San Francisco, United States
Duration: Jan 27 2024 → …

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume12821
ISSN (Print)1605-7422

Conference

ConferenceVisualizing and Quantifying Drug Distribution in Tissue VIII 2024
Country/TerritoryUnited States
CitySan Francisco
Period01/27/24 → …

Keywords

  • Brillouin
  • Confocal microscopy
  • Elastic properties
  • in vitro Imaging
  • Multimodal imaging
  • Photodynamic therapy
  • Spectroscopy
  • Tissue elasticity

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