Invasive curvularia infection in pediatric patients with hematologic malignancy identified by fungal sequencing

Yeh Chung Chang, Erin Graf, Abby M. Green

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Curvularia is a saprophytic dematiaceous mold and a rare human pathogen. Here, we report three severely immunocompromised pediatric patients who developed invasive Curvularia infection. Diagnosis was achieved or confirmed in all cases by fungal ribosome sequencing, which hastened species identification and targeted treatment for the patients reported. There are no treatment guidelines for invasive Curvularia infection, though we report three patients who were cured of their infection through a combination of surgical resection and various anti-fungal therapies, indicating a relatively low virulence and good prognosis in comparison to other angioinvasive molds.

Original languageEnglish
Pages (from-to)87-91
Number of pages5
JournalJournal of the Pediatric Infectious Diseases Society
Volume8
Issue number1
DOIs
StatePublished - Jan 1 2019
Externally publishedYes

Keywords

  • Curvularia
  • Fungal sequencing
  • Leukemia

Fingerprint Dive into the research topics of 'Invasive curvularia infection in pediatric patients with hematologic malignancy identified by fungal sequencing'. Together they form a unique fingerprint.

  • Cite this