Introduction and history

Vikas R. Dharnidharka; Michael Green; Steven A. Webber; Ralf Ulrich Trappe

doi:10.1007/978-3-030-65403-0_1

Introduction and history

Vikas R. Dharnidharka, Michael Green, Steven A. Webber, Ralf Ulrich Trappe

Research output: Chapter in Book/Report/Conference proceeding › Foreword/postscript

Abstract

Posttransplant lymphoproliferative disorders (PTLDs) straddle the disciplines of immunology, infection, and malignancy. PTLDs are a major complication of transplantation, such that its study is a discipline by itself. The study of PTLD has led to advances that have ramifications beyond transplantation. Early observations revealed that lightening of immunosuppression could lead to regression in some cases, eliminating the hopelessness of the word "lymphoma." While PTLD treatments and outcomes have improved, responses remain suboptimal, and the need for additional strategies for prevention and treatment remains.

Original language	English
Title of host publication	Post-Transplant Lymphoproliferative Disorders
Publisher	Springer International Publishing
Pages	1-6
Number of pages	6
ISBN (Electronic)	9783030654030
ISBN (Print)	9783030654023
DOIs	https://doi.org/10.1007/978-3-030-65403-0_1
State	Published - Feb 11 2021

Keywords

B cell
Epstein-Barr virus
Immunology
Infection
Malignancy
Posttransplant lymphoproliferative disorder

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10.1007/978-3-030-65403-0_1

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abstract = "Posttransplant lymphoproliferative disorders (PTLDs) straddle the disciplines of immunology, infection, and malignancy. PTLDs are a major complication of transplantation, such that its study is a discipline by itself. The study of PTLD has led to advances that have ramifications beyond transplantation. Early observations revealed that lightening of immunosuppression could lead to regression in some cases, eliminating the hopelessness of the word {"}lymphoma.{"} While PTLD treatments and outcomes have improved, responses remain suboptimal, and the need for additional strategies for prevention and treatment remains.",

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AU - Dharnidharka, Vikas R.

AU - Green, Michael

AU - Webber, Steven A.

AU - Trappe, Ralf Ulrich

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PY - 2021/2/11

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AB - Posttransplant lymphoproliferative disorders (PTLDs) straddle the disciplines of immunology, infection, and malignancy. PTLDs are a major complication of transplantation, such that its study is a discipline by itself. The study of PTLD has led to advances that have ramifications beyond transplantation. Early observations revealed that lightening of immunosuppression could lead to regression in some cases, eliminating the hopelessness of the word "lymphoma." While PTLD treatments and outcomes have improved, responses remain suboptimal, and the need for additional strategies for prevention and treatment remains.

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KW - Epstein-Barr virus

KW - Immunology

KW - Infection

KW - Malignancy

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BT - Post-Transplant Lymphoproliferative Disorders

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ER -

Introduction and history

Abstract

Keywords

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