TY - JOUR
T1 - Intravenous albunex during dobutamine stress echocardiography
T2 - Enhanced localization of left ventricular endocardial borders
AU - Falcone, Rita A.
AU - Marcovitz, Pamela A.
AU - Perez, Julio E.
AU - Dittrich, Howard C.
AU - Hopkins, William E.
AU - Armstrong, William F.
N1 - Funding Information:
From the Divisions of Cardiology, Departments of Medicine, %he University of Michigan, Ann Arbor; bWashingto'University, St. Louis; and Cthe University of California, San Diego. Supported by a grant from Molecular Biosystems, San Diego, Calif. Received for publication Nov. 18, 1994; accepted Jan. 5, 1995, Reprint requests: William F. Armstrong~ MD, Echocardiography Laboratory, University of Michigan, 1500 East Medical Center Dr., Ann Arbor, MI 48109 Copyright © 1995 by Mosby-Year Book, Inc. 0002-8703/95/$3.00 + 0 4/1/64234
PY - 1995/8
Y1 - 1995/8
N2 - Albunex is an intravenous contrast agent that opacifies the left ventricle (LV).This study evaluated the effect of Albunex on the enhancement of LV endocardial border localization during dobutamine stress echocardiography (DSE). Albunex was infused in 30 patients at baseline and with low- and high-dosage dobutamine. Apical two- and four-chamber views were divided into six segments each, and enhancement of LV border localization was compared with precontrast images graded as follows: 0 = none; 1 = faint; or 2 = optimal. The mean grade and percentage of segments with optimal localization of LV endocardial borders were determined. There was a significant increase in enhancement with low- and high-dosage dobutamine when compared with baseline. Of 179 segments with suboptimal enhancement at baseline, 137 (77%) became optimal during DSE with Albunex. We conclude that Albunex improves localization of LV endocardial borders and that this localization is enhanced during DSE.
AB - Albunex is an intravenous contrast agent that opacifies the left ventricle (LV).This study evaluated the effect of Albunex on the enhancement of LV endocardial border localization during dobutamine stress echocardiography (DSE). Albunex was infused in 30 patients at baseline and with low- and high-dosage dobutamine. Apical two- and four-chamber views were divided into six segments each, and enhancement of LV border localization was compared with precontrast images graded as follows: 0 = none; 1 = faint; or 2 = optimal. The mean grade and percentage of segments with optimal localization of LV endocardial borders were determined. There was a significant increase in enhancement with low- and high-dosage dobutamine when compared with baseline. Of 179 segments with suboptimal enhancement at baseline, 137 (77%) became optimal during DSE with Albunex. We conclude that Albunex improves localization of LV endocardial borders and that this localization is enhanced during DSE.
UR - http://www.scopus.com/inward/record.url?scp=0029126702&partnerID=8YFLogxK
U2 - 10.1016/0002-8703(95)90437-9
DO - 10.1016/0002-8703(95)90437-9
M3 - Article
C2 - 7631604
AN - SCOPUS:0029126702
SN - 0002-8703
VL - 130
SP - 254
EP - 258
JO - American Heart Journal
JF - American Heart Journal
IS - 2
ER -