Intraretinal circuit formation

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

The circuitry of the vertebrate retina is organized into discrete layers or laminae, giving rise to a close relationship between structure and function. This article highlights the major developmental events that lead to the assembly of intraretinal circuits, focusing on how developing retinal neurons elaborate their pre- and postsynaptic processes within their appropriate laminae, and on the synaptogenic events between the various retinal cell types. Comparisons across two major vertebrate models, mouse and zebrafish, will be made where possible to underscore common or species-specific developmental trends and mechanisms responsible for the wiring of retinal circuits.

Original languageEnglish
Title of host publicationEncyclopedia of the Eye
PublisherElsevier
Pages461-470
Number of pages10
ISBN (Electronic)9780123742032
ISBN (Print)9780123741981
DOIs
StatePublished - Jan 1 2010

Keywords

  • Amacrine cells
  • Bipolar cells
  • Dendritic and axonal development
  • Horizontal cells
  • Photoreceptors
  • Retinal activity
  • Retinal circuits
  • Retinal ganglion cells
  • Retinal lamination
  • Synaptogenesis

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