Intraoperative awareness: From neurobiology to clinical practice

George A. Mashour, Beverley A. Orser, Michael S. Avidan

Research output: Contribution to journalReview articlepeer-review

79 Scopus citations


Intraoperative awareness is defined by both consciousness and explicit memory of surgical events. Although electroencephalographic techniques to detect and prevent awareness are being investigated, no method has proven uniformly reliable. The lack of a standard intraoperative monitor for the brain likely reflects our insufficient understanding of consciousness and memory. In this review, the authors discuss the neurobiology of consciousness and memory, as well as the incidence, risk factors, sequelae, and prevention of intraoperative awareness.

Original languageEnglish
Pages (from-to)1218-1233
Number of pages16
Issue number5
StatePublished - May 2011


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