Intracellular site of synthesis of soluble blood group substance

Stuart Kornfeld; Rosalind Kornfeld; Victor Ginsburg

doi:10.1016/0003-9861(65)90147-5

Intracellular site of synthesis of soluble blood group substance

Stuart Kornfeld
, Rosalind Kornfeld
, Victor Ginsburg

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

The intracellular distribution of soluble blood group substance in hog gastric mucosa was investigated. The microsomal fraction contains 1-3% of the total intracellular blood group substance. Labeling experiments in vivo show this small pool to be newly synthesized material and the precursor of other intracellular pools. Attempts to detect a nucleotide-linked, fucose-containing oligosaccharide intermediate in the synthesis of the heterosaccharide chains of blood group substance were unsuccessful.

Original language	English
Pages (from-to)	1-7
Number of pages	7
Journal	Archives of Biochemistry and Biophysics
Volume	110
Issue number	1
DOIs	https://doi.org/10.1016/0003-9861(65)90147-5
State	Published - Apr 1965

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title = "Intracellular site of synthesis of soluble blood group substance",

abstract = "The intracellular distribution of soluble blood group substance in hog gastric mucosa was investigated. The microsomal fraction contains 1-3\% of the total intracellular blood group substance. Labeling experiments in vivo show this small pool to be newly synthesized material and the precursor of other intracellular pools. Attempts to detect a nucleotide-linked, fucose-containing oligosaccharide intermediate in the synthesis of the heterosaccharide chains of blood group substance were unsuccessful.",

author = "Stuart Kornfeld and Rosalind Kornfeld and Victor Ginsburg",

year = "1965",

month = apr,

doi = "10.1016/0003-9861(65)90147-5",

language = "English",

volume = "110",

pages = "1--7",

journal = "Archives of Biochemistry and Biophysics",

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TY - JOUR

T1 - Intracellular site of synthesis of soluble blood group substance

AU - Kornfeld, Stuart

AU - Kornfeld, Rosalind

AU - Ginsburg, Victor

PY - 1965/4

Y1 - 1965/4

N2 - The intracellular distribution of soluble blood group substance in hog gastric mucosa was investigated. The microsomal fraction contains 1-3% of the total intracellular blood group substance. Labeling experiments in vivo show this small pool to be newly synthesized material and the precursor of other intracellular pools. Attempts to detect a nucleotide-linked, fucose-containing oligosaccharide intermediate in the synthesis of the heterosaccharide chains of blood group substance were unsuccessful.

AB - The intracellular distribution of soluble blood group substance in hog gastric mucosa was investigated. The microsomal fraction contains 1-3% of the total intracellular blood group substance. Labeling experiments in vivo show this small pool to be newly synthesized material and the precursor of other intracellular pools. Attempts to detect a nucleotide-linked, fucose-containing oligosaccharide intermediate in the synthesis of the heterosaccharide chains of blood group substance were unsuccessful.

UR - https://www.scopus.com/pages/publications/50549219146

U2 - 10.1016/0003-9861(65)90147-5

DO - 10.1016/0003-9861(65)90147-5

M3 - Article

C2 - 14321853

AN - SCOPUS:50549219146

SN - 0003-9861

VL - 110

SP - 1

EP - 7

JO - Archives of Biochemistry and Biophysics

JF - Archives of Biochemistry and Biophysics

IS - 1

ER -

Intracellular site of synthesis of soluble blood group substance

Abstract

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