Intracellular site of synthesis of soluble blood group substance

Stuart Kornfeld, Rosalind Kornfeld, Victor Ginsburg

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


The intracellular distribution of soluble blood group substance in hog gastric mucosa was investigated. The microsomal fraction contains 1-3% of the total intracellular blood group substance. Labeling experiments in vivo show this small pool to be newly synthesized material and the precursor of other intracellular pools. Attempts to detect a nucleotide-linked, fucose-containing oligosaccharide intermediate in the synthesis of the heterosaccharide chains of blood group substance were unsuccessful.

Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalArchives of Biochemistry and Biophysics
Issue number1
StatePublished - Apr 1965


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