Interventional inflammatory bowel disease: current and future practice

Benjamin Clement, Juan Reyes Genere

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose of reviewInflammatory bowel diseases (IBD) are associated with several well described neoplastic and structural complications. Increasing disease prevalence, healthcare barriers, and medication refractory phenotypes contribute to ongoing complications despite significant strides in medical management. Enhancements in endoscopic technology and techniques have allowed a minimally invasive approach for what has historically required surgery. In this article, we review the current and future landscape of endoscopic IBD intervention.Recent findingsEndoscopic resection is the first line for managing conventional and complex colitis-associated dysplasia. Evidence supporting endoscopic submucosal dissection is mounting, yet there is a paucity of studies evaluating modified endoscopic mucosal resection techniques or hybrid endoscopic submucosal dissection. We also have more clarity in how best to approach fibrostenotic disease, as we learn how to position endoscopic stricturotomy and stenting, relative to balloon dilation. Finally, applications in managing penetrating and postsurgical complications have been described, but still require further study.SummaryWhile important knowledge gaps still exist, the application of endoscopic therapies in IBD is more refined, especially within the management of colitis-associated dysplasia and strictures. The indications for endoscopy in perianal disease and other penetrating manifestations of Crohn's disease presents exciting opportunities for growth.

Original languageEnglish
Pages (from-to)276-284
Number of pages9
JournalCurrent opinion in gastroenterology
Volume40
Issue number4
DOIs
StatePublished - Jul 1 2024

Keywords

  • Crohn's stricture
  • colitis-associated dysplasia
  • inflammatory bowel disease
  • perianal Crohn's disease
  • therapeutic endoscopy

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