TY - JOUR
T1 - Interrater reliability of the clinical dementia rating in a multicenter trial
AU - Rockwood, Kenneth
AU - Strang, David
AU - MacKnight, Chris
AU - Downer, Robert
AU - Morris, John C.
PY - 2000/5
Y1 - 2000/5
N2 - OBJECTIVE: To test the interrater reliability of the Clinical Dementia Rating (CDR) in a multicenter clinical trial. DESIGN: Observational study. SETTING: Training session for a multicenter trial of milameline, a direct muscarinic agonist, in the treatment of Alzheimer's disease. PARTICIPANTS: Twenty-four raters (physicians and nurses) familiar with drug trials and expert in the care of patients with Alzheimer's disease. METHODS: Independent scoring of the CDR using four videotaped CDR interviews. OUTCOME MEASURE: Interrater reliability, as tested by the Kappa statistic RESULTS: The overall interrater reliability was 0.62. Within the CDR domains, the global kappas ranged from 0.33 ± 0.06 to 0.88 ± 0.06. CONCLUSIONS: The data support moderate to high overall interrater reliability but show important difficulties in the reliable assessment of early dementia.
AB - OBJECTIVE: To test the interrater reliability of the Clinical Dementia Rating (CDR) in a multicenter clinical trial. DESIGN: Observational study. SETTING: Training session for a multicenter trial of milameline, a direct muscarinic agonist, in the treatment of Alzheimer's disease. PARTICIPANTS: Twenty-four raters (physicians and nurses) familiar with drug trials and expert in the care of patients with Alzheimer's disease. METHODS: Independent scoring of the CDR using four videotaped CDR interviews. OUTCOME MEASURE: Interrater reliability, as tested by the Kappa statistic RESULTS: The overall interrater reliability was 0.62. Within the CDR domains, the global kappas ranged from 0.33 ± 0.06 to 0.88 ± 0.06. CONCLUSIONS: The data support moderate to high overall interrater reliability but show important difficulties in the reliable assessment of early dementia.
KW - Alzheimer's disease
KW - Clinical dementia rating
KW - Reliability
UR - http://www.scopus.com/inward/record.url?scp=0034063066&partnerID=8YFLogxK
U2 - 10.1111/j.1532-5415.2000.tb05004.x
DO - 10.1111/j.1532-5415.2000.tb05004.x
M3 - Article
C2 - 10811551
AN - SCOPUS:0034063066
VL - 48
SP - 558
EP - 559
JO - Journal of the American Geriatrics Society
JF - Journal of the American Geriatrics Society
SN - 0002-8614
IS - 5
ER -