Keyphrases
Mammalian Target of Rapamycin (mTOR)
100%
Astrocytes
100%
Rapamycin
100%
Genetically Engineered Mouse Models
100%
Cell Growth Inhibition
100%
Rapamycin Treatment
60%
Phosphoinositide 3-kinase (PI3K)
40%
Treatment Response
20%
Clinical Trials
20%
Tumor Growth
20%
Clinically Significant
20%
Neurofibromatosis Type 1 (NF-1)
20%
Dose Effect
20%
Ki-67
20%
Exponential Relationship
20%
Preclinical Data
20%
Durable Response
20%
Glial Cells
20%
Kinase Inhibition
20%
Suppression Effect
20%
Optic Pathway Glioma
20%
Tumor Proliferation
20%
Mammalian Target of Rapamycin Inhibition
20%
Jagged1
20%
Tumor Inhibition
20%
Targeted Inhibition
20%
Mammalian Target of Rapamycin Pathway
20%
Pathway Inhibitors
20%
Akt Activation
20%
P-STAT3
20%
Targeting Effect
20%
Growth Suppression
20%
4E-BP1
20%
Glial Cell Proliferation
20%
Phospho-S6
20%
Rapamycin Analogs
20%
Biochemistry, Genetics and Molecular Biology
Mouse Model
100%
Cell Growth
100%
Astrocyte
100%
Growth Inhibition
100%
Genetically Engineered Mouse Strain
100%
Mechanistic Target of Rapamycin
100%
Tumor Progression
50%
Phosphoinositide 3-Kinase
33%
Clinical Trial
16%
Mediator
16%
Cell Proliferation
16%
Microglia
16%
Glial Cells
16%
STAT3
16%
Immunology and Microbiology
Mouse Model
100%
Sirolimus
100%
Cell Growth
100%
Astrocyte
100%
Growth Inhibition
100%
Genetically Engineered Mouse Strain
100%
Mediator
6%
STAT3
6%
Microglia
6%
Cell Proliferation
6%
Pharmacology, Toxicology and Pharmaceutical Science
Mouse Model
100%
Rapamycin
100%
Genetically Engineered Mouse Strain
100%
Mammalian Target of Rapamycin
100%
Tumor Growth
33%
Phosphatidylinositol 3 Kinase
22%
Biological Marker
22%
Clinical Trial
11%
Neurofibromatosis Type 1
11%
Optic Nerve Glioma
11%
Protein Jagged 1
11%
Neuroscience
Astrocyte
100%
Cell Growth
100%
Mammalian Target of Rapamycin
100%
Sirolimus
100%
In Vivo
22%
Phosphoinositide 3-Kinase
22%
Microglia
11%
In Vitro
11%
Cell Proliferation
11%
Neurofibromatosis Type 1
11%
Glial Cells
11%
STAT3
11%
Protein Jagged 1
11%