TY - JOUR
T1 - Interpretation of intrinsic and extrinsic structural relations by path analysis
T2 - Theory and applications to assortative mating
AU - Cloninger, C. Robert
N1 - Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1980/10
Y1 - 1980/10
N2 - The theory of path analysis is extended by considering a multivariate system of correlations from a dual perspective. Intrinsic factors exert a unidirectional influence on both the variance and covariance of dependent factors. In contrast, extrinsic factors have a bidirectional influence on the covariance structure of both antecedent and dependent factors and do not influence intrinsic variability. The mathematical model assumes a formally complete linear system of unitary factors. A coefficient is defined to quantify the influence of adventitious associations and is called a copath. Copaths are compared to path coefficients and to correlations due to common antecedents. The chain properties of these coefficients are derived along with a general formula and computational algorithm. The method is illustrated for multifactorial inheritance in extended pedigrees in the presence of different types of assortative mating.
AB - The theory of path analysis is extended by considering a multivariate system of correlations from a dual perspective. Intrinsic factors exert a unidirectional influence on both the variance and covariance of dependent factors. In contrast, extrinsic factors have a bidirectional influence on the covariance structure of both antecedent and dependent factors and do not influence intrinsic variability. The mathematical model assumes a formally complete linear system of unitary factors. A coefficient is defined to quantify the influence of adventitious associations and is called a copath. Copaths are compared to path coefficients and to correlations due to common antecedents. The chain properties of these coefficients are derived along with a general formula and computational algorithm. The method is illustrated for multifactorial inheritance in extended pedigrees in the presence of different types of assortative mating.
UR - http://www.scopus.com/inward/record.url?scp=0019217067&partnerID=8YFLogxK
U2 - 10.1017/S0016672300019765
DO - 10.1017/S0016672300019765
M3 - Article
AN - SCOPUS:0019217067
SN - 0016-6723
VL - 36
SP - 133
EP - 145
JO - Genetical Research
JF - Genetical Research
IS - 2
ER -