Atherosclerosis is driven by the release of cytokines from macrophages, and the β isoform of interleukin-1 (IL-1β) is a prime suspect in disease progression. Freigang et al. (2013) now suggest that IL-1α, a close relative, is selectively induced by fatty acids independent of the inflammasome to promote vascular inflammation.

Original languageEnglish
Pages (from-to)614-616
Number of pages3
JournalCell metabolism
Issue number5
StatePublished - Nov 5 2013


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