Interdependence of parkin-mediated mitophagy and mitochondrial fission in adult mouse hearts

Keyphrases

• Ablating 8%
• Ablation 8%
• Adult Cardiac 8%
• Adult Mice 16%
• Adult Mouse Heart 100%
• Adverse Cardiac Remodeling 8%
• Adverse Effects 8%
• Cardiac Fibrosis 8%
• Cardiac Ischemia 8%
• Cardiac Phenotype 8%
• Cardiomyopathy 16%
• Dynamin-related Protein 1 (Drp1) 58%
• Ejection Performance 8%
• Enlargement 8%
• Fission 8%
• Gene Deletion 8%
• Germline 8%
• HyPer 8%
• Interdependence 100%
• Knock-in Mouse Model 8%
• LC3-II 8%
• Microtubule-associated Protein 1 Light Chain 3 8%
• Mitochondria 8%
• Mitochondrial Content 8%
• Mitochondrial Depletion 8%
• Mitochondrial Fission 100%
• Mitochondrial Proteins 8%
• Mitophagy 16%
• Mouse Heart 8%
• Myocytes 50%
• Normal Heart 25%
• Overexpression 8%
• Parkin 100%
• PINK1/Parkin-mediated Mitophagy 100%
• Quality Control 8%
• Replacement Fibrosis 8%
• Sequestosome 1 8%
• Ubiquitination 8%

Biochemistry, Genetics and Molecular Biology

• Cardiac Muscle Cell 87%
• Dynamin 87%
• Gene Deletion 12%
• Germ Cell 12%
• Heart Ventricle Ejection 12%
• Knockout Mouse 12%
• Light Chain 12%
• Messenger RNA 12%
• Microtubule-Associated Protein 12%
• Mitochondrial Fission 100%
• Mitochondrial Protein 12%
• Mitochondrion 12%
• Mitophagy 100%
• Quality Control 12%
• Sequestosome 1 12%
• Synapsin I 100%
• Ubiquitination 12%
• Upregulation 12%