Interaction of uropathogenic Escherichia coli with host uroepithelium

Research output: Contribution to journalReview article

52 Scopus citations

Abstract

Investigation into the pathogenesis of Escherichia coli urinary tract infection has provided numerous insights into the mechanisms by which bacteria adhere, grow and persist in association with host tissue. Many molecular details concerning the interaction of these bacteria with their host have been elucidated, and the murine model of cystitis has generated a new paradigm by which acute and recurrent urinary tract infections may proceed. These advances could potentially result in the development of novel vaccines and therapies for this very costly disease.

Original languageEnglish
Pages (from-to)54-59
Number of pages6
JournalCurrent Opinion in Microbiology
Volume8
Issue number1
DOIs
StatePublished - Feb 2005

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