Interaction of uropathogenic Escherichia coli with host uroepithelium

Andrew L. Kau; David A. Hunstad; Scott J. Hultgren

doi:10.1016/j.mib.2004.12.001

Interaction of uropathogenic Escherichia coli with host uroepithelium

Andrew L. Kau, David A. Hunstad, Scott J. Hultgren

Research output: Contribution to journal › Review article › peer-review

62 Scopus citations

Abstract

Investigation into the pathogenesis of Escherichia coli urinary tract infection has provided numerous insights into the mechanisms by which bacteria adhere, grow and persist in association with host tissue. Many molecular details concerning the interaction of these bacteria with their host have been elucidated, and the murine model of cystitis has generated a new paradigm by which acute and recurrent urinary tract infections may proceed. These advances could potentially result in the development of novel vaccines and therapies for this very costly disease.

Original language	English
Pages (from-to)	54-59
Number of pages	6
Journal	Current Opinion in Microbiology
Volume	8
Issue number	1
DOIs	https://doi.org/10.1016/j.mib.2004.12.001
State	Published - Feb 2005

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title = "Interaction of uropathogenic Escherichia coli with host uroepithelium",

abstract = "Investigation into the pathogenesis of Escherichia coli urinary tract infection has provided numerous insights into the mechanisms by which bacteria adhere, grow and persist in association with host tissue. Many molecular details concerning the interaction of these bacteria with their host have been elucidated, and the murine model of cystitis has generated a new paradigm by which acute and recurrent urinary tract infections may proceed. These advances could potentially result in the development of novel vaccines and therapies for this very costly disease.",

author = "Kau, {Andrew L.} and Hunstad, {David A.} and Hultgren, {Scott J.}",

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AB - Investigation into the pathogenesis of Escherichia coli urinary tract infection has provided numerous insights into the mechanisms by which bacteria adhere, grow and persist in association with host tissue. Many molecular details concerning the interaction of these bacteria with their host have been elucidated, and the murine model of cystitis has generated a new paradigm by which acute and recurrent urinary tract infections may proceed. These advances could potentially result in the development of novel vaccines and therapies for this very costly disease.

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Interaction of uropathogenic Escherichia coli with host uroepithelium

Abstract

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