Intense 18F-fluoride accumulation in liver metastases from a neuroendocrine tumor after peptide receptor radionuclide therapy

Cyprian Świȩtaszczyk, Vikas Prasad, Richard P. Baum

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

A 48-year-old female patient with a liver-metastasizing neuroendocrine tumor of pancreas underwent restaging with F-fluoride PET/CT after peptide receptor radionuclide therapy. The study detected 4 intense activity enhancements in the liver. These corresponded to 4 of altogether 9 liver metastatic lesions. The fluoride-positive lesions were calcified. Additionally, in pretherapeutic PET scans with 18F-FDG as well as with 68Ga-DOTA-NOC, they presented with doughnut sign and with more avid accumulation of 18F-FDG.

Original languageEnglish
Pages (from-to)e82-e83
JournalClinical nuclear medicine
Volume37
Issue number4
DOIs
StatePublished - Apr 2012

Keywords

  • Ga-DOTA-NOC receptor PET/CT
  • calcification
  • fluoride PET/CT
  • liver metastases
  • neuroendocrine tumor
  • pancreas
  • peptide receptor radionuclide therapy

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