Keyphrases
Pathogenic Variants
100%
Glucose-6-phosphatase (G6Pase)
100%
Integrative Analysis
100%
AlphaFold
100%
Catalytic Subunit
44%
Active Sites
33%
Glycogen Storage Disease Type II (GSDII)
33%
Side Chain
22%
Phosphate Binding
22%
Glucose Homeostasis
11%
Gluconeogenesis
11%
Molecular Dynamics Simulation
11%
Hydrolysis
11%
Endoplasmic Reticulum
11%
In Situ
11%
Lumen
11%
Hydrogen Bonds (H-bonds)
11%
Hepatic Glucose Production
11%
Biochemical Assay
11%
Integral Membrane Protein
11%
Missense Variants
11%
Thermodynamics
11%
Missense mutation
11%
Severe Hypoglycemia
11%
Glycogenolysis
11%
Binding Interaction
11%
Conserved Residues
11%
Structural Organization
11%
In Silico Prediction
11%
Substrate Binding
11%
Inactivating mutation
11%
Van Der Waals
11%
Lipid Phosphatase
11%
Thermodynamic Stability
11%
Non-catalytic
11%
Side-chain Packing
11%
Atomic Interactions
11%
Catalytic Intermediates
11%
Biochemistry, Genetics and Molecular Biology
Glucose 6-Phosphatase
100%
Glucose 6-Phosphate
100%
Enzyme Active Site
50%
Active Site
37%
Gluconeogenesis
25%
Glucose Homeostasis
12%
Enzymatic Hydrolysis
12%
Missense
12%
Missense Mutation
12%
Glycogenolysis
12%
Integral Membrane Protein
12%
Phosphatidate Phosphatase
12%
Computer Simulation
12%