Integrating informatics: And high-content screening to find a cure for spinal cord injury: Selecting a LIMS for CNS regeneration

Vance Lemmon, William Buchser, Don Crossett

Research output: Contribution to specialist publicationArticle

Abstract

High-content screening is being counted on to uncover signaling pathways, genes, compounds, or drugs that can be used to promote nerve growth has been reported. The screening pipeline includes solid experimental techniques combined with instrumentation and analytical tools. High-content screening offers an ideal way to identify genes; molecular pathways; and, ultimately, drugs that can promote the regeneration of CNS axons. In order to minimize costs and engage the laboratory staff, a workshop approach was recommended to create a solution that fit the needs of the end users. Benefits of the workshop approach include reduced cost of implementation, user acceptance, client ownership of the system, and flexibility to expand/modify functionality as needs change. The LIMS is helping to accelerate discovery for the Miami Project to Cure Paralysis in its high-content screening laboratories.

Original languageEnglish
Pages24-26
Number of pages3
Volume42
No1
Specialist publicationAmerican Laboratory
StatePublished - Jan 1 2010
Externally publishedYes

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