Abstract

Genetic variants in chromosome 19 are strongly associated with frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). Ma et al.1 and Brown et al.2 demonstrated that this association was driven by variation in UNC13A and that the underlying mechanism involved aberrant TDP-43 localization, a known pathological hallmark of both diseases

Original languageEnglish
Pages (from-to)226-227
Number of pages2
JournalMed
Volume3
Issue number4
DOIs
StatePublished - Apr 8 2022

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