TY - JOUR
T1 - Integrating a rapid diagnostic test and antimicrobial stewardship
T2 - Optimizing discharge antibiotics in skin and soft tissue infections
AU - Yu, Diana
AU - Stach, Leslie
AU - Newland, Jason G.
AU - Selvarangan, Rangaraj
AU - Goldman, Jennifer
PY - 2016/11/28
Y1 - 2016/11/28
N2 - A rapid test to detect methicillin resistance in Staphylococcus aureus through the penicillin-binding protein 2a antigen was introduced for pediatric patients hospitalized for purulent skin and soft tissue infections. Integration of this test with physician education and stewardship guidance improved targeted antibiotic use for infections caused by methicillin-susceptible S. aureus (44%-80%, P < 0.001), including when final culture results were not available.
AB - A rapid test to detect methicillin resistance in Staphylococcus aureus through the penicillin-binding protein 2a antigen was introduced for pediatric patients hospitalized for purulent skin and soft tissue infections. Integration of this test with physician education and stewardship guidance improved targeted antibiotic use for infections caused by methicillin-susceptible S. aureus (44%-80%, P < 0.001), including when final culture results were not available.
KW - Antimicrobial stewardship
KW - Pediatrics
KW - Rapid diagnostics
KW - Skin and soft tissue infections
KW - Staphylococcus aureus
UR - http://www.scopus.com/inward/record.url?scp=84988599450&partnerID=8YFLogxK
U2 - 10.1097/INF.0000000000001332
DO - 10.1097/INF.0000000000001332
M3 - Article
C2 - 27649364
AN - SCOPUS:84988599450
SN - 0891-3668
VL - 35
SP - 1362
EP - 1364
JO - Pediatric Infectious Disease Journal
JF - Pediatric Infectious Disease Journal
IS - 12
ER -