INTEGRATE-neo: A pipeline for personalized gene fusion neoantigen discovery

Jin Zhang, Elaine R. Mardis, Christopher Maher

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

Motivation: While high-throughput sequencing (HTS) has been used successfully to discover tumor-specific mutant peptides (neoantigens) from somatic missense mutations, the field currently lacks a method for identifying which gene fusions may generate neoantigens. Results: We demonstrate the application of our gene fusion neoantigen discovery pipeline, called INTEGRATE-Neo, by identifying gene fusions in prostate cancers that may produce neoantigens.

Original languageEnglish
Pages (from-to)555-557
Number of pages3
JournalBioinformatics
Volume33
Issue number4
DOIs
StatePublished - Feb 15 2017

Fingerprint Dive into the research topics of 'INTEGRATE-neo: A pipeline for personalized gene fusion neoantigen discovery'. Together they form a unique fingerprint.

  • Cite this