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Insights into the Pathogenesis and Treatment of Krabbe Disease
Ernesto R.oque Bongarzone
, Maria L.uisa Escolar
, Steven J.ames Gray
, Tal Kafri
, Charles H.erman Vite
, Mark S.teven Sands
Center of Regenerative Medicine
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
Institute of Clinical and Translational Sciences (ICTS)
Siteman Cancer Center
Bursky Center for Human Immunology & Immunotherapy Programs (CHiiPs)
DBBS - Molecular Cell Biology
DBBS - Neurosciences
DBBS - Molecular Genetics and Genomics
Hope Center for Neurological Disorders
Intellectual and Developmental Disabilities Research Center (IDDRC)
Division of Oncology
Research output
:
Contribution to journal
›
Review article
›
peer-review
26
Scopus citations
Overview
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Keyphrases
Krabbe Disease
100%
Galactocerebrosidase
71%
Murine Model
28%
Psychosine
28%
Disease Progression
14%
Hematopoietic Stem Cell Transplantation
14%
Inherited Disease
14%
Oligodendrocyte
14%
Dysregulation
14%
Lipids
14%
Infiltration
14%
Peripheral Nervous System
14%
Lymphocytes
14%
Myelin
14%
Schwann Cells
14%
Juvenile-onset
14%
Preclinical Data
14%
Motor Dysfunction
14%
Cognitive Decline
14%
Adult-onset
14%
Canine Model
14%
Primate Model
14%
Globoid Cell Leukodystrophy
14%
Pathogenic Mechanism
14%
Galactosylsphingosine
14%
Monocyte-derived Macrophages
14%
Lysosomal Enzymes
14%
Fatal Infection
14%
Disorganization
14%
Intractable Seizures
14%
Globoid Cell
14%
New Drug Targets
14%
Premature Death
14%
Inflammatory Chemokines
14%
Glycolipids
14%
Galactosylated
14%
Multinucleated
14%
White Matter Disease
14%
Central Nervous System Cells
14%
α-galactosylceramide (α-GalCer)
14%
Neuroscience
Krabbe Disease
100%
Galactosylceramidase
71%
Psychosine
42%
Leukodystrophy
14%
Oligodendrocyte
14%
Central Nervous System
14%
Disorientation
14%
Myelin
14%
Macrophage
14%
Stereotypic Movement Disorder
14%
Peripheral Nervous System
14%
Schwann Cell
14%
Nervous System Cell
14%
Chemokine
14%
Lysosome Enzyme
14%
White Matter Disease
14%
Cognitive Dysfunction
14%
Glycolipid
14%
Galactosylceramide
14%
Proinflammatory Cytokine
14%
Lymphocyte
14%
Hematopoietic Cell
14%