TY - JOUR
T1 - Inotropic response to dobutamine in elderly patients with decompensated congestive heart failure
AU - Rich, Michael W.
AU - Imburgia, Michael
N1 - Funding Information:
From the Scott and White Clinic, 3005 El Camino Drive, Temple, Texas 76502. This study was supported in part by the Robert A. Welch Foundation, Houston, Mr. Louis Pearce of Houston, Mr. and Mrs. Lamar L. Walker of Bryan, Dr. and Mrs. K. L. Nelson of Bryan, Texas, Mrs. Caroline Ann Bailey of Oklahoma City, Oklahoma, and Mr. and Mrs. Frank Mayborn of Temple, Texas. Manuscript received May 9, 1989; revised manuscript received and accepted December 7, 1989.
PY - 1990/2/15
Y1 - 1990/2/15
N2 - One of the principal effects of aging on the cardiovascular system is an attenuation of responsiveness to (8-adrenergic stimulation.1 Dobutamine, a synthetic catecholamine with potent inotropic properties mediated through stimulation of cardiac β receptors, has been shown to be less effective in elderly patients with either normal left ventricular function2 or congestive heart failure (CHF) complicating acute myocardial infarction.3 However, although CHF is a leading cause of hospitalization in the elderly, the response to dobutamine in elderly patients with severe, decompensated CHF has not previously been described.
AB - One of the principal effects of aging on the cardiovascular system is an attenuation of responsiveness to (8-adrenergic stimulation.1 Dobutamine, a synthetic catecholamine with potent inotropic properties mediated through stimulation of cardiac β receptors, has been shown to be less effective in elderly patients with either normal left ventricular function2 or congestive heart failure (CHF) complicating acute myocardial infarction.3 However, although CHF is a leading cause of hospitalization in the elderly, the response to dobutamine in elderly patients with severe, decompensated CHF has not previously been described.
UR - http://www.scopus.com/inward/record.url?scp=0025058876&partnerID=8YFLogxK
U2 - 10.1016/0002-9149(90)90823-J
DO - 10.1016/0002-9149(90)90823-J
M3 - Article
C2 - 2305692
AN - SCOPUS:0025058876
SN - 0002-9149
VL - 65
SP - 519
EP - 521
JO - The American journal of cardiology
JF - The American journal of cardiology
IS - 7
ER -