Inotropic response to dobutamine in elderly patients with decompensated congestive heart failure

Michael W. Rich, Michael Imburgia

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

One of the principal effects of aging on the cardiovascular system is an attenuation of responsiveness to (8-adrenergic stimulation.1 Dobutamine, a synthetic catecholamine with potent inotropic properties mediated through stimulation of cardiac β receptors, has been shown to be less effective in elderly patients with either normal left ventricular function2 or congestive heart failure (CHF) complicating acute myocardial infarction.3 However, although CHF is a leading cause of hospitalization in the elderly, the response to dobutamine in elderly patients with severe, decompensated CHF has not previously been described.

Original languageEnglish
Pages (from-to)519-521
Number of pages3
JournalThe American journal of cardiology
Volume65
Issue number7
DOIs
StatePublished - Feb 15 1990
Externally publishedYes

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