Innate-like T cells: A promising asset in anti-cancer immunity

Martina Molgora; Marco Colonna

doi:10.1016/j.ccell.2022.05.017

Innate-like T cells: A promising asset in anti-cancer immunity

Martina Molgora, Marco Colonna

Research output: Contribution to journal › Comment/debate

4 Scopus citations

Abstract

In Nature, Chou et al. identify a subset of innate-like αβ T cells with high cytotoxic potential that accumulate in tumors and elicit an anti-tumor response. Given their capacity to maintain an activation state without undergoing exhaustion, these innate-like T cells may represent effective therapeutic agents for cell-based approaches.

Original language	English
Pages (from-to)	714-716
Number of pages	3
Journal	Cancer Cell
Volume	40
Issue number	7
DOIs	https://doi.org/10.1016/j.ccell.2022.05.017
State	Published - Jul 11 2022

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title = "Innate-like T cells: A promising asset in anti-cancer immunity",

abstract = "In Nature, Chou et al. identify a subset of innate-like αβ T cells with high cytotoxic potential that accumulate in tumors and elicit an anti-tumor response. Given their capacity to maintain an activation state without undergoing exhaustion, these innate-like T cells may represent effective therapeutic agents for cell-based approaches.",

author = "Martina Molgora and Marco Colonna",

note = "Publisher Copyright: {\textcopyright} 2022",

year = "2022",

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T2 - A promising asset in anti-cancer immunity

AU - Molgora, Martina

AU - Colonna, Marco

PY - 2022/7/11

Y1 - 2022/7/11

N2 - In Nature, Chou et al. identify a subset of innate-like αβ T cells with high cytotoxic potential that accumulate in tumors and elicit an anti-tumor response. Given their capacity to maintain an activation state without undergoing exhaustion, these innate-like T cells may represent effective therapeutic agents for cell-based approaches.

AB - In Nature, Chou et al. identify a subset of innate-like αβ T cells with high cytotoxic potential that accumulate in tumors and elicit an anti-tumor response. Given their capacity to maintain an activation state without undergoing exhaustion, these innate-like T cells may represent effective therapeutic agents for cell-based approaches.

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U2 - 10.1016/j.ccell.2022.05.017

DO - 10.1016/j.ccell.2022.05.017

M3 - Comment/debate

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AN - SCOPUS:85133875967

SN - 1535-6108

VL - 40

SP - 714

EP - 716

JO - Cancer Cell

JF - Cancer Cell

IS - 7

ER -

Innate-like T cells: A promising asset in anti-cancer immunity

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