Inhibitory control in children with frontal infarcts related to sickle cell disease

Shawn E. Christ; Asif Moinuddin; Robert C. McKinstry; Michael DeBaun; Desirée A. White

doi:10.1080/09297040500346563

Inhibitory control in children with frontal infarcts related to sickle cell disease

Shawn E. Christ, Asif Moinuddin, Robert C. McKinstry, Michael DeBaun, Desirée A. White

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Evidence from past studies indicates that children with traumatic brain injury experience difficulties with inhibitory control. Less is known about inhibitory control in children with frontal brain injury related to cerebral infarction. We compared the inhibitory performance of children with frontal infarcts related to sickle cell disease with that of a control group of children with sickle cell disease but no history of cerebral infarction. On a stimulus-response reversal task, children with frontal infarcts made significantly more accuracy errors in the inhibitory condition than controls. Findings from this study and from previous research suggest that impairments in inhibitory control are common following frontal injury in a range of pediatric populations.

Original language	English
Pages (from-to)	132-141
Number of pages	10
Journal	Child Neuropsychology
Volume	13
Issue number	2
DOIs	https://doi.org/10.1080/09297040500346563
State	Published - Mar 1 2007

Keywords

Children
Cognition
Executive ability
Frontal cortex
Inhibitory control
Neuropsychology
Sickle cell disease

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10.1080/09297040500346563

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abstract = "Evidence from past studies indicates that children with traumatic brain injury experience difficulties with inhibitory control. Less is known about inhibitory control in children with frontal brain injury related to cerebral infarction. We compared the inhibitory performance of children with frontal infarcts related to sickle cell disease with that of a control group of children with sickle cell disease but no history of cerebral infarction. On a stimulus-response reversal task, children with frontal infarcts made significantly more accuracy errors in the inhibitory condition than controls. Findings from this study and from previous research suggest that impairments in inhibitory control are common following frontal injury in a range of pediatric populations.",

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AU - DeBaun, Michael

AU - White, Desirée A.

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AB - Evidence from past studies indicates that children with traumatic brain injury experience difficulties with inhibitory control. Less is known about inhibitory control in children with frontal brain injury related to cerebral infarction. We compared the inhibitory performance of children with frontal infarcts related to sickle cell disease with that of a control group of children with sickle cell disease but no history of cerebral infarction. On a stimulus-response reversal task, children with frontal infarcts made significantly more accuracy errors in the inhibitory condition than controls. Findings from this study and from previous research suggest that impairments in inhibitory control are common following frontal injury in a range of pediatric populations.

KW - Children

KW - Cognition

KW - Executive ability

KW - Frontal cortex

KW - Inhibitory control

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Inhibitory control in children with frontal infarcts related to sickle cell disease

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