Inhibition of vascular smooth muscle G protein-coupled receptor kinase 2 enhances α_1D-adrenergic receptor constriction

Keyphrases

• Constriction 100%
• Vascular Smooth muscle Cells 100%
• Adrenergic Receptors 100%
• GRK2 100%
• Receptor-mediated 16%
• Blood Pressure 16%
• Vasoconstriction 16%
• Two-kidney One-clip 16%
• Hypertension 8%
• G Protein-coupled Receptor 8%
• MRNA Level 8%
• Improved Outcomes 8%
• In Situ 8%
• Receptor Function 8%
• Lymphocytes 8%
• Attenuation 8%
• Norepinephrine Levels 8%
• Vasodilation 8%
• Human Animals 8%
• Elevated Blood Pressure 8%
• Pharmacological Assays 8%
• Gene Ablation 8%
• Renal Artery Stenosis 8%
• Effective Tool 8%
• Stenosis Model 8%
• Heart Failure Outcomes 8%
• Human Hypertension 8%
• Peptide Inhibition 8%

Biochemistry, Genetics and Molecular Biology

• Adrenergic Receptor 100%
• G Protein-Coupled Receptor Kinase 100%
• Blood Pressure 27%
• Vasoconstriction 18%
• Messenger RNA 9%
• Kinase 9%
• Phosphotransferase 9%
• Lymphocyte 9%
• G Protein Coupled Receptor 9%
• Agonist 9%
• Animal Model 9%
• Vasodilatation 9%
• Serine 9%
• Noradrenalin Blood Level 9%
• Noradrenalin Level 9%

Pharmacology, Toxicology and Pharmaceutical Science

• Adrenergic Receptor 100%
• G Protein Coupled Receptor Kinase 2 100%
• Disease 9%
• Phosphotransferase 9%
• Elevated Blood Pressure 9%
• Heart Failure 9%
• Serine 9%
• G Protein Coupled Receptor 9%
• Noradrenalin 9%
• Kidney Artery Stenosis 9%