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Keyphrases
Mammalian Target of Rapamycin (mTOR)
100%
Breast Cancer Cells
100%
Rapamycin
100%
Tamoxifen Response
100%
Breast Carcinoma
75%
Mammalian Target of Rapamycin Inhibition
75%
Tamoxifen Resistance
75%
Tumor
25%
Growth Inhibition
25%
Breast Cancer Cell Lines
25%
Synergism
25%
Resistant Cancer Cells
25%
Chemotherapy Resistance
25%
Poor Prognosis
25%
Estrogen
25%
Estrogen Receptor
25%
Breast Tumor
25%
Downstream Targets
25%
Novel Mechanism
25%
Transcriptional Activity
25%
Constitutively Active
25%
Biological Response
25%
Luciferase
25%
Reporter Gene Assay
25%
MTOR Inhibitor
25%
Xenograft Model
25%
Esters
25%
Serine-threonine Kinase
25%
Mammalian Target of Rapamycin Pathway
25%
Blockage
25%
Co-treatment
25%
Estrogen Response Element
25%
Implications for Future
25%
Akt Activation
25%
MCF-7
25%
Induced Resistance
25%
Aggressive Phenotype
25%
AKT Pathway
25%
Hormone Resistance
25%
Phosphatidylinositol 3-kinase/Akt Signaling
25%
CCI-779
25%
Akt Kinase
25%
Medicine and Dentistry
Cancer Cell
100%
Breast Cancer
100%
Tamoxifen
100%
Mechanistic Target of Rapamycin
100%
Protein Kinase B
100%
Rapamycin
44%
Breast Carcinoma
33%
In Vitro
22%
Phosphoinositide 3-Kinase
11%
Antiinfective Agent
11%
Clinical Study
11%
Reporter Gene
11%
Estrogen Receptor
11%
Tumor
11%
Breast Tumor
11%
Xenograft
11%
Luciferase
11%
Cell Signaling Pathway
11%
Mammalian Target of Rapamycin Inhibitor
11%
Breast Cancer Cell Line
11%
Akt Signaling
11%
Protein Kinase B
11%
Casein Kinase
11%
MCF-7
11%
Estrogen Responsive Element
11%
Pharmacology, Toxicology and Pharmaceutical Science
Breast Cancer
100%
Mammalian Target of Rapamycin
100%
Tamoxifen
100%
Rapamycin
50%
Breast Carcinoma
37%
Malignant Neoplasm
12%
Phosphatidylinositol 3 Kinase
12%
Synergism
12%
Clinical Study
12%
Chemotherapy
12%
Estrogen Receptor
12%
Breast Tumor
12%
Antiinfective Agent
12%
Luciferase
12%
Mammalian Target of Rapamycin Inhibitor
12%
Protein Kinase B
12%
Casein Kinase
12%
Biochemistry, Genetics and Molecular Biology
Cancer Cell
100%
Mechanistic Target of Rapamycin
100%
Protein Kinase B
100%
Luciferase
11%
Phosphoinositide 3-Kinase
11%
Reporter Gene
11%
Estrogen Receptor
11%
Clinical Study
11%
Akt Signaling
11%
Estrogen Responsive Element
11%
Casein Kinase
11%
Protein Kinase B
11%
Immunology and Microbiology
Sirolimus
100%
Cancer Cell
100%
In Vitro
16%
Synergism
8%
Reporter Gene
8%
Xenograft
8%
Akt Signaling
8%
Breast Cancer Cell Line
8%
Estrogen Responsive Element
8%
Serine
8%
Threonine
8%
Susceptibility
8%