Inhibition of human erythrocyte calpain I by novel quinolinecarboxamides

Todd L. Graybill; Roland E. Dolle; Irennegbe K. Osifo; Stanley J. Schmidt; Jill S. Gregory; Alex L. Harris; Matthew S. Miller

doi:10.1016/0960-894X(95)00041-Q

Inhibition of human erythrocyte calpain I by novel quinolinecarboxamides

Todd L. Graybill, Roland E. Dolle, Irennegbe K. Osifo, Stanley J. Schmidt, Jill S. Gregory, Alex L. Harris, Matthew S. Miller

Center for Drug Discovery

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

1,4-Dihydro-4-oxo-3-quinolinecarboxamides are a class of non-peptide reversible inhibitor of human erythrocyte Calpain I. The preparation and in vitro evaluation of these compounds are discussed.

Original language	English
Pages (from-to)	387-392
Number of pages	6
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	5
Issue number	4
DOIs	https://doi.org/10.1016/0960-894X(95)00041-Q
State	Published - Feb 16 1995

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@article{5a47fa22ec794368a10ed91e88e4fc95,

title = "Inhibition of human erythrocyte calpain I by novel quinolinecarboxamides",

abstract = "1,4-Dihydro-4-oxo-3-quinolinecarboxamides are a class of non-peptide reversible inhibitor of human erythrocyte Calpain I. The preparation and in vitro evaluation of these compounds are discussed.",

author = "Graybill, {Todd L.} and Dolle, {Roland E.} and Osifo, {Irennegbe K.} and Schmidt, {Stanley J.} and Gregory, {Jill S.} and Harris, {Alex L.} and Miller, {Matthew S.}",

year = "1995",

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doi = "10.1016/0960-894X(95)00041-Q",

language = "English",

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T1 - Inhibition of human erythrocyte calpain I by novel quinolinecarboxamides

AU - Graybill, Todd L.

AU - Dolle, Roland E.

AU - Osifo, Irennegbe K.

AU - Schmidt, Stanley J.

AU - Gregory, Jill S.

AU - Harris, Alex L.

AU - Miller, Matthew S.

PY - 1995/2/16

Y1 - 1995/2/16

N2 - 1,4-Dihydro-4-oxo-3-quinolinecarboxamides are a class of non-peptide reversible inhibitor of human erythrocyte Calpain I. The preparation and in vitro evaluation of these compounds are discussed.

AB - 1,4-Dihydro-4-oxo-3-quinolinecarboxamides are a class of non-peptide reversible inhibitor of human erythrocyte Calpain I. The preparation and in vitro evaluation of these compounds are discussed.

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U2 - 10.1016/0960-894X(95)00041-Q

DO - 10.1016/0960-894X(95)00041-Q

M3 - Article

AN - SCOPUS:0028795381

SN - 0960-894X

VL - 5

SP - 387

EP - 392

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 4

ER -

Inhibition of human erythrocyte calpain I by novel quinolinecarboxamides

Abstract

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