Inhibition of human erythrocyte calpain I by novel quinolinecarboxamides

Todd L. Graybill, Roland E. Dolle, Irennegbe K. Osifo, Stanley J. Schmidt, Jill S. Gregory, Alex L. Harris, Matthew S. Miller

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


1,4-Dihydro-4-oxo-3-quinolinecarboxamides are a class of non-peptide reversible inhibitor of human erythrocyte Calpain I. The preparation and in vitro evaluation of these compounds are discussed.

Original languageEnglish
Pages (from-to)387-392
Number of pages6
JournalBioorganic and Medicinal Chemistry Letters
Issue number4
StatePublished - Feb 16 1995


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