TY - JOUR
T1 - Influenza pathogenesis
T2 - The effect of host factors on severity of disease
AU - Gounder, Anshu P.
AU - Boon, Adrianus C.M.
N1 - Publisher Copyright:
Copyright © 2019 by The American Association of Immunologists, Inc.
PY - 2019/1/15
Y1 - 2019/1/15
N2 - Influenza viruses continue to be a major global health threat. Severity and clinical outcome of influenza disease is determined by both viral and host factors. Viral factors have long been the subject of intense research and many molecular determinants have been identified. However, research into the host factors that protect or predispose to severe and fatal influenza A virus infections is lagging. The goal of this review is to highlight the recent insights into host determinants of influenza pathogenesis.
AB - Influenza viruses continue to be a major global health threat. Severity and clinical outcome of influenza disease is determined by both viral and host factors. Viral factors have long been the subject of intense research and many molecular determinants have been identified. However, research into the host factors that protect or predispose to severe and fatal influenza A virus infections is lagging. The goal of this review is to highlight the recent insights into host determinants of influenza pathogenesis.
UR - http://www.scopus.com/inward/record.url?scp=85059929903&partnerID=8YFLogxK
U2 - 10.4049/jimmunol.1801010
DO - 10.4049/jimmunol.1801010
M3 - Review article
C2 - 30617115
AN - SCOPUS:85059929903
SN - 0022-1767
VL - 202
SP - 341
EP - 350
JO - Journal of Immunology
JF - Journal of Immunology
IS - 2
ER -