Inflammatory pseudotumors in the buccal tissues of children

Inflammatory pseudotumor is a nonneoplastic lesion of unknown origin. Most cases occur in the respiratory tract or orbit. This study reports three cases, all involving children, of rapidly enlarging masses in the soft tissues of the oral cavity. They were initially suspected to be malignant but proved to be inflammatory pseudotumors. The histologic appearance was that of a fibroproliferative process containing chronic inflammatory cells. The pleomorphism and mitotic activity of the fibroblasts were worrisome features. Regression without sequelae occurred in all three patients.