Inflammatory conditions of the salivary glands: Sjøgren’s disease, IgG4-related disease, and sarcoidosis

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations


• Systemic inflammatory conditions may affect the salivary glands.• The clinical presentation of inflammatory diseases of the salivary glands is often non-specific and clinical suspicion is required for diagnosis, especially when present in isolation. Symptoms can include dry mouth, salivary gland swelling, and pain localizing to the salivary gland. • Sjøgren’s syndrome is an autoimmune disease characterized by sicca syndrome and lymphocytic infiltration of salivary and lacrimal glands.• IgG4-related disease is a recently defined entity resulting in salivary gland swelling and dysfunction. • Sarcoidosis is a granulomatous disease chiefly presenting with cough and dyspnea, which rarely affects the salivary glands. • Management of systemic inflammatory conditions is primarily medical, under the direction of medical specialists (rheumatology, pulmonary, etc); however, surgery may play a role in both diagnosis and management of these conditions or their complications.

Original languageEnglish
Title of host publicationGland-Preserving Salivary Surgery
Subtitle of host publicationA Problem-Based Approach
PublisherSpringer International Publishing
Number of pages7
ISBN (Electronic)9783319583358
ISBN (Print)9783319583334
StatePublished - Jan 1 2018


  • IgG4-related disease
  • Labial salivary biopsy
  • Sarcoidosis
  • Sialendoscopy
  • Sjøgren’s syndrome


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