Inflammatory comorbidities: to train or not to train?

Suhas Bobba, Shabaana A. Khader

Research output: Contribution to journalShort surveypeer-review

Abstract

Inflammatory stimuli reprogram innate immune cells to generate rigorous responses to future challenge with heterologous stimuli through trained immunity. Li et al. show that training of hematopoietic stem cells (HSCs) in the bone marrow primes cells to generate more inflammatory myeloid progeny and, thereby, mechanistically links inflammatory comorbidities.

Original languageEnglish
Pages (from-to)420-422
Number of pages3
JournalTrends in Immunology
Volume43
Issue number6
DOIs
StatePublished - Jun 2022

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